Article

Perinatal Fentanyl Exposure Drives Enduring Addiction Risk and Central Amygdala Gene Dysregulation

2025-05-21

Abstract excerpt

The use of fentanyl and other opioids during pregnancy is a pressing public health issue due to its association with Neonatal Opioid Withdrawal Syndrome (NOWS) and long-term neurobehavioral deficits. Human epidemiologic studies are confounded by both genetic and environmental factors that differ between exposed and unexposed children. We developed a novel rat model of perinatal fentanyl exposure to characterize NO...

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Literature Corpus work: d18ba0df-f9d0-56b8-bcb3-8113f8cdde0e
DOI: 10.1101/2025.05.20.655167

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