Article

Estrogen withdrawal alters oxytocin signaling in the paraventricular hypothalamus and dorsal raphe nucleus to increase postpartum anxiety

2020-06-17

Abstract excerpt

<h4>Background</h4> Estrogen increases dramatically during pregnancy, but quickly drops below pre-pregnancy levels at birth and remains suppressed during the postpartum period. Clinical and rodent work suggests that this postpartum drop in estrogen results in an “estrogen withdrawal” state that is related to changes in affect, mood, and behavior. Most studies examining the effect of estrogen withdrawal on the bra...

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Literature Corpus work: 77fd1fd5-fd48-56cc-b1da-cdc4538d2bdc
DOI: 10.1101/2020.06.16.154492

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