Article

Repetitive and compulsive behavior after Early-Life-Pain associated with reduced long-chain sphingolipid species

2023-05-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Pain in early life may affect cortical development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of "early-life-pain" (ELP) using mice with transgenic expression of channelrhodopsin-2 (ChR2) under control of the <italic>Advillin</italic> (<italic>Avil</italic>) promoter, which drives expression of transgenes predominantly in isolectin...

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Literature Corpus work: 4c1c40ce-1db1-5101-a904-496e4da1982e
DOI: 10.21203/rs.3.rs-2765061/v1

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