Article

A Novel Mouse Model of Chronic Primary Pain Conditions that Integrates Clinically Relevant Genetic and Environmental Factors

2022-12-19

Abstract excerpt

Chronic primary pain conditions (CPPCs) affect over 100 million people, predominantly women. Yet, they remain ineffectively treated due, in large part, to lack of valid animal models with translational relevance. Here, we characterized a novel mouse model of CPPCs that integrated clinically-relevant genetic (catechol-o-methyltransferase; COMT knockdown) and environmental (stress and minor injury) factors. Compared...

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Literature Corpus work: 5c1e5c7d-e92a-5900-b0e6-6025a40ebf54
DOI: 10.1101/2022.12.18.520949

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