Article
The interplay between DNA methylation and sequence divergence in recent human evolution
2015-03-03
Abstract excerpt
DNA methylation is a key regulatory mechanism in mammalian genomes. Despite the increasing knowledge about this epigenetic modification, the understanding of human epigenome evolution is in its infancy. We used whole genome bisulfite sequencing to study DNA methylation and nucleotide divergence between human and great apes. We identified 360 and 210 differentially hypo- and hypermethylated regions (DMRs) in humans...
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Identifiers and source
- Literature Corpus work
- 4bd4b3d2-6fb8-57b5-a663-7b15034d6ce6
- DOI
- 10.1101/015966