Article
Harnessing epigenetics to study human evolution.
Current opinion in genetics & development - 1 Jun 2020
Mathov Yoav, Batyrev Daniel, Meshorer Eran, Carmel Liran
Abstract excerpt
Recent advances in ancient DNA extraction and high-throughput sequencing technologies enabled the high-quality sequencing of archaic genomes, including the Neanderthal and the Denisovan. While comparisons with modern humans revealed both archaic-specific and human-specific sequence changes, in the absence of gene expression information, understanding the functional implications of such genetic variations remains...
Topics
- DNA Methylation
- Epigenesis, Genetic
- Evolution, Molecular
- Genetic Variation
- Genome, Human
- Humans
