Article
Worldwide patterns of human epigenetic variation.
Nature ecology & evolution - 1 Oct 2017
Carja Oana, MacIsaac Julia L, Mah Sarah M, Henn Brenna M, Kobor Michael S, Feldman Marcus W, Fraser Hunter B
Abstract excerpt
DNA methylation is an epigenetic modification, influenced by both genetic and environmental variation, that plays a key role in transcriptional regulation and many organismal phenotypes. Although patterns of DNA methylation have been shown to differ between human populations, it remains to be determined how epigenetic diversity relates to the patterns of genetic and gene expression variation at a global scale....
Topics
- DNA Methylation
- Epigenesis, Genetic
- Gene Expression
- Genetic Variation
- Genotype
- Humans
