Article

Comprehensive Study of Germline Mutations and Double-Hit Events in Esophageal Squamous Cell Cancer

2021-02-06

Abstract excerpt

Esophageal squamous cell cancer (ESCC) is the eighth most common cancer around the world. Several reports have focused on somatic mutations and common germline mutations in ESCC. However, the contributions of pathogenic germline alterations in cancer susceptibility genes (CSGs), highly frequently mutated CSGs, and pathogenically mutated CSG-related pathways in ESCC remain unclear. We obtained data on 571 ESCC case...

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Literature Corpus work: 4bcbb083-6447-560c-8ec5-4c30040ced2d
DOI: 10.1101/2021.02.04.21251116

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