Back to search

Article

Differential predictive value of resident memory CD8 <sup>+</sup> T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy

2024-03-12

Abstract excerpt

A high density of resident memory T cells (T RM ) in tumors correlates with improved clinical outcomes in immunotherapy-treated patients. However, in preclinical models, only some subpopulations of T RM are associated with cancer vaccine efficacy. We identified two main T RM subpopulations in tumor-infiltrating lymphocytes derived from non-small cell lung cancer (NSCLC) patients: one co-expressing CD103 and CD...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b589b2c5-a6c0-5912-b094-cd7625d8632a
DOI
10.1101/2024.03.07.583820
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Differential predictive value of resident memory CD8 <sup>+</sup> T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapyDOI 10.1101/2024.03.07.583820
Tumor-resident memory T cells as a biomarker of the response to cancer immunotherapySemantic proximity
Resident memory T cells, critical components in tumor immunology.Semantic proximity
Phenotype of circulating tumor-reactive T cells predicts immune checkpoint inhibitor response in non-small cell lung cancer.Semantic proximity
Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancerSemantic proximity
Contribution of resident and circulating precursors to tumor-infiltrating CD8 <sup>+</sup> T cell populations in non-small cell lung cancer patientsSemantic proximity
Tissue-resident memory CD8+ T cells in cancer immunology and immunotherapy.Semantic proximity
Phenotypic Differences of CD103+ Tissue-Resident Memory T Cells Associated with Various Cancers.Semantic proximity
CD8+ TILs in NSCLC differentiate into TEMRA via a bifurcated trajectory: deciphering immunogenicity of tumor antigensSemantic proximity
Mapping the immune landscape in small cell lung cancer unveils a distinct tumor-reactive CD8+ T cell molecular signatureSemantic proximity
High density of TCF1+ stem-like tumor-infiltrating lymphocytes is associated with favorable disease-specific survival in NSCLCSemantic proximity
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumoursSemantic proximity
Resident Memory T Cells and Their Effect on CancerSemantic proximity
Select a neighboring publication to make it the new centre.