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Article

TET2-Driven Demethylation of ANG promotes Angiogenesis and Malignant transformation in Oligodendroglioma

2026-01-22

Abstract excerpt

<title>Abstract</title> <p>Oligodendrogliomas (OG) are indolent yet inevitably progressive gliomas in which angiogenesis is tightly linked to malignant transformation, but the underlying epigenetic mechanisms remain unclear. By integrating public datasets of primary and malignant transformed OG specimens, patient-derived cell lines and orthotopic xenograft models, we identify angiogenin (ANG) as a key pro-angioge...

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Literature Corpus work
4bbafef8-8de3-5ce3-8c5f-1d5e25ea51bc
DOI
10.21203/rs.3.rs-8533226/v1
Open publication

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TET2-Driven Demethylation of ANG promotes Angiogenesis and Malignant transformation in OligodendrogliomaDOI 10.21203/rs.3.rs-8533226/v1
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