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Article

Tie2/TEK modulates the interaction of glioma and brain tumor stem cells with endothelial cells and promotes an invasive phenotype.

Oncotarget - 1 Dec 2010

Liu Dan, Martin Vanesa, Fueyo Juan, Lee Ok-Hee, Xu Jing, Cortes-Santiago Nahir, Alonso Marta M, Aldape Kenneth, Colman Howard, Gomez-Manzano Candelaria

Abstract excerpt

Malignant gliomas are the prototype of highly infiltrative tumors and this characteristic is the main factor for the inevitable tumor recurrence and short survival after most aggressive therapies. The aberrant communication between glioma cells and tumor microenvironment represents one of the major factors regulating brain tumor dispersal. Our group has previously reported that the tyrosine kinase receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21321379
DOI: 10.18632/oncotarget.204
PMCID: PMC3100177

Genes

TEK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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