Article

Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype

2022-12-02

Abstract excerpt

Obesity has been linked with numerous health issues as well as an increased risk of breast cancer. Although effects of direct obesity in patient outcomes is widely studied, effects of exposure to obesity-related systemic influences in utero has been overlooked. In this study, we investigated the effect of multigenerational obesity on epithelial cell migration and invasion using decellularized breast tissues expla...

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Literature Corpus work: 4bb16429-d72f-5f82-9d5f-78038582c342
DOI: 10.1101/2022.11.29.518205

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