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The Dynamic Interaction between Extracellular Matrix Remodeling and Breast Tumor Progression

29 Apr 2021

Abstract excerpt

Desmoplastic tumors correspond to a unique tissue structure characterized by the abnormal deposition of extracellular matrix. Breast tumors are a typical example of this type of lesion, a property that allows its palpation and early detection. Fibrillar type I collagen is a major component of tumor desmoplasia and its accumulation is causally linked to tumor cell survival and metastasis. For many years, the...

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PMID: 33946660
DOI: 10.3390/cells10051046

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