Article

Obesity modifies cell fate plasticity of <i>Pdgfrα-</i> expressing adipocyte progenitors to promote an aberrant mammary microenvironment

2023-12-29

Abstract excerpt

Excess fat gain culminating in obesity is a mounting global pandemic associated with a myriad of diseases including a higher risk of developing multiple cancers such as breast cancer. The underlying biological basis for obesity-linked breast cancer is attributed to alterations in adipose tissue-derived endocrine, metabolic and inflammatory factors. However, the precise cell types responsible for generating a cance...

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Literature Corpus work: 660b85d4-ddb2-52e9-88c4-e0cfd2d6b0e3
DOI: 10.1101/2023.12.28.573587

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