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Article

Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype.

Biomaterials - 1 Jun 2023

Amens Jensen N, Bahçecioğlu Gökhan, Dwyer Kiera, Yue Xiaoshan S, Stack M Sharon, Hilliard Tyvette S, Zorlutuna Pinar

Abstract excerpt

Obesity has been linked with numerous health issues as well as an increased risk of breast cancer. Although effects of direct obesity in patient outcomes is widely studied, effects of exposure to obesity-related systemic influences in utero have been overlooked. In this study, we investigated the effect of multigenerational obesity on epithelial cell migration and invasion using decellularized breast tissues...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37062214
DOI: 10.1016/j.biomaterials.2023.122110
PMCID: PMC10192205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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