Article

Obesity modifies cell fate plasticity of Pdgfrα-expressing adipocyte progenitors to promote an aberrant mammary microenvironment

2024-02-19

Abstract excerpt

<title>Abstract</title> <p>Excess fat gain culminating in obesity is a mounting global pandemic associated with a myriad of diseases including a higher risk of developing multiple cancers such as breast cancer. The underlying biological basis for obesity-linked breast cancer is attributed to alterations in adipose tissue-derived endocrine, metabolic and inflammatory factors. However, the precise cell types respon...

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Literature Corpus work: da4d8bc4-7ab3-5814-97c9-b35387c710db
DOI: 10.21203/rs.3.rs-3826560/v1

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