Article

Polyploid cancer cells reveal signatures of chemotherapy resistance

2024-08-23

Abstract excerpt

Therapeutic resistance in cancer significantly contributes to mortality, with many patients eventually experiencing recurrence after initial treatment responses. Recent studies have identified therapy-resistant large polyploid cancer cells in patient tissues, particularly in late-stage prostate cancer, linking them to advanced disease and relapse. Here, we analyzed bone marrow aspirates from 44 advanced prostate c...

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Literature Corpus work: 4bb12056-ce0e-5dc0-9d82-a52207eeeaa3
DOI: 10.1101/2024.08.19.608632

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