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Polyploid cancer cells reveal signatures of chemotherapy resistance

2024-10-14

Abstract excerpt

<title>Abstract</title> <p>Therapeutic resistance in cancer significantly contributes to mortality, with many patients eventually experiencing recurrence after initial treatment responses. Recent studies have identified therapy-resistant large polyploid cancer cells in patient tissues, particularly in late-stage prostate cancer, linking them to advanced disease and relapse. Here, we analyzed bone marrow aspirates...

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Literature Corpus work: 40e4d116-2408-54c2-8e55-87fb2edd5aa7
DOI: 10.21203/rs.3.rs-4921634/v1

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