Article

A digital PCR primer/probe library for physical tumor burden assessment through tumor-informed longitudinal ctDNA monitoring

2026-05-15

Abstract excerpt

<title>Abstract</title> <p>Circulating tumor DNA (ctDNA) monitoring is informative for longitudinal physical tumor burden (PTB) assessment. However, NGS-based ctDNA monitoring is limited by sensitivity, cost, and turnaround time in clinical practice. We developed OTS-Probes, an off-the-shelf digital PCR (dPCR) primer/probe library prepared for more than 1,000 frequently registered somatic mutations. Oligonucleoti...

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Literature Corpus work: 4ba13baa-b39d-5f30-8d0c-427db5fc6687
DOI: 10.21203/rs.3.rs-9417145/v1

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