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Clinical Circulating Tumor DNA Testing for Precision Oncology.

Cancer research and treatment - 1 Apr 2023

Kim Hyunji, Park Kyoung Un

Abstract excerpt

Circulating tumor DNA (ctDNA) is the portion of the cell-free DNA in the blood of cancer patients released from tumor cells via apoptosis, necrosis, or active release. From 10 mL of blood, the 4-5 mL of plasma obtained from a cancer patient contains 5-10 ng/mL of ctDNA. The plasma contains not only ctDNA of tumor origin, but also DNA from normal cells or clonal hematopoiesis. Another characteristic of ctDNA is...

Topics

Humans
Neoplasms
Circulating Tumor DNA
Precision Medicine
Medical Oncology
Biomarkers, Tumor
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36915242
DOI: 10.4143/crt.2022.1026
PMCID: PMC10101787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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