Article
Clinical Circulating Tumor DNA Testing for Precision Oncology.
Cancer research and treatment - 1 Apr 2023
Kim Hyunji, Park Kyoung Un
Abstract excerpt
Circulating tumor DNA (ctDNA) is the portion of the cell-free DNA in the blood of cancer patients released from tumor cells via apoptosis, necrosis, or active release. From 10 mL of blood, the 4-5 mL of plasma obtained from a cancer patient contains 5-10 ng/mL of ctDNA. The plasma contains not only ctDNA of tumor origin, but also DNA from normal cells or clonal hematopoiesis. Another characteristic of ctDNA is...
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