Article
Genetic profiling of cancer with circulating tumor DNA analysis.
Journal of genetics and genomics = Yi chuan xue bao - 20 Feb 2018
Lu Ling, Bi Junqin, Bao Liming
Abstract excerpt
Circulating cell-free tumor DNA (ctDNA) in the blood is DNA released from apoptotic, circulating, and living tumor cells. ctDNA is about 140 nt in length and has a half-life of about 1.5 h. ctDNA analysis provides a noninvasive means to assess the genetic profile of cancer in real time. With the advent of molecular technologies, including digital PCR and massively parallel sequencing (MPS), ctDNA analysis has...
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