Article
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors.
Molecular diagnosis & therapy - 1 Nov 2023
Zhao Jianhua, Reuther Jacquelyn, Scozzaro Kaylee, Hawley Megan, Metzger Emily, Emery Matthew, Chen Ingrid, Barbosa Michelle, Johnson Laura, O'Connor Alijah, Washburn Mike, Hartje Luke, Reckase Erik, Johnson Verity, Zhang Yuhua, Westheimer Emily, O'Callaghan William, Malani Nirav, Chesh Adrian, Moreau Michael, Daber Robert
Abstract excerpt
BACKGROUND: Highly sensitive molecular assays have been developed to detect plasma-based circulating tumor DNA (ctDNA), and emerging evidence suggests their clinical utility for monitoring minimal residual disease and recurrent disease, providing prognostic information, and monitoring therapy responses in patients with solid tumors. The Invitae Personalized Cancer Monitoring™ assay uses a patient-specific,...
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