Article

Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences

2018-03-12

Abstract excerpt

The Pan-cancer Analysis of Whole Genomes (PCAWG) project provides an unprecedented opportunity to comprehensively characterize a vast set of uniformly annotated coding and non-coding mutations present in thousands of cancer genomes. Classical models of cancer progression posit that only a small number of these mutations strongly drive tumor progression and that the remaining ones (termed “putative passengers”) are...

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Literature Corpus work: 4ba0c82e-2a68-5121-8c93-8eacc6250ed6
DOI: 10.1101/280446

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