Article

Chronic elevation of 1.25(OH) <sub>2</sub> D enhances cholesterol excretion through coordinated regulation of hepatic and intestinal elimination pathways

2026-05-13

Abstract excerpt

Cholesterol elimination in mammals depends largely on the biliary secretion of cholesterol and its conversion to bile acids, followed by their fecal loss. Human studies suggest an association between blood vitamin D levels and blood cholesterol; however, the mechanistic impact of sustained elevation of 1,25(OH) 2 D 3 (active vitamin D) on cholesterol flux remains unclear. Here, we used two complementary mouse mo...

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Literature Corpus work: 4b6aae65-a41c-530c-914e-57418b4d6216
DOI: 10.64898/2026.05.11.724189

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Chronic elevation of 1.25(OH) <sub>2</sub> D enhances cholesterol excretion through coordinated regulation of hepatic and intestinal elimination pathwaysDOI 10.64898/2026.05.11.724189Read

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