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Article

Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs).

BMC genomics - 1 Jan 2015

Handelman Samuel K, Seweryn Michal, Smith Ryan M, Hartmann Katherine, Wang Danxin, Pietrzak Maciej, Johnson Andrew D, Kloczkowski Andrzej, Sadee Wolfgang

Abstract excerpt

BACKGROUND: Over the past 50,000 years, shifts in human-environmental or human-human interactions shaped genetic differences within and among human populations, including variants under positive selection. Shaped by environmental factors, such variants influence the genetics of modern health, disease, and treatment outcome. Because evolutionary processes tend to act on gene regulation, we test whether regulatory...

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Identifiers

PMID: 26111110
DOI: 10.1186/1471-2164-16-S8-S8
PMCID: PMC4480832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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