Article

SlytheRINs: using graph parameters and residue interaction networks to analyze protein dynamics and structural ensembles

2026-02-28

Abstract excerpt

<h4>ABSTRACT</h4> Establishing the relationship between protein structure and functional behavior remains a significant challenge. The recognition that proteins are inherently dynamic, with functions often dependent on conformational changes, is increasingly accepted. Among computational approaches for elucidating protein properties, Residue Interaction Network (RIN) analysis has emerged as a powerful tool. Howev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4ad8c33d-234d-57ec-b98b-5fb1bbd2d23f
DOI: 10.64898/2026.02.26.708270

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SlytheRINs: using graph parameters and residue interaction networks to analyze protein dynamics and structural ensemblesDOI 10.64898/2026.02.26.708270Read

AutoGraph: Autonomous Graph Based Clustering of Small-Molecule ConformationsSemantic proximity Read

Conformational dynamics of nonsynonymous variants at protein interfaces reveals disease association.Semantic proximity Read

LNGCN: a distance-aware continuous-time graph framework for PPI prioritization in experimental screeningSemantic proximity Read

SCREEN: a graph-based contrastive learning tool to infer catalytic residues and assess mutation tolerance in enzymesSemantic proximity Read

Molecular mechanisms of catalytic inhibition for active site mutations in glucose-6-phosphatase catalytic subunit 1 linked to glycogen storage diseaseSemantic proximity Read

Coupling between Protein Stability and Catalytic Activity Determines Pathogenicity of G6PD Variants.Semantic proximity Read

Conserved water molecules as structural ligands modulating pathogenic variation in human protein binding sitesSemantic proximity Read

How Aberrant <i>N</i> -Glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic ViewSemantic proximity Read

Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII.Semantic proximity Read

Protein Dynamics at Different Timescales Unlock Access to Hidden Post-Translational Modification SitesSemantic proximity Read

Integrative conformational ensembles of Sic1 using different initial pools and optimization methodsSemantic proximity Read

Correlation assessment among clinical phenotypes, expression analysis and molecular modeling of 14 novel variations in the human galactose-1-phosphate uridylyltransferase gene.Semantic proximity Read