Article

Integrative conformational ensembles of Sic1 using different initial pools and optimization methods

2022-04-01

Abstract excerpt

<h4>ABSTRACT</h4> Intrinsically disordered proteins play key roles in regulatory protein interactions, but their detailed structural characterization remains challenging. Here we calculate and compare conformational ensembles for the disordered protein Sic1 from yeast, starting from initial ensembles that were generated either by statistical sampling of the conformational landscape, or by molecular dynamics simul...

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Literature Corpus work: 455faec0-0185-5d66-a102-98882a49f715
DOI: 10.1101/2022.04.01.486785

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