Article

Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity

2023-01-27

Abstract excerpt

<h4>ABSTRACT</h4> Behavioral pattern separation and cognitive flexibility are essential cognitive abilities which are disrupted in many brain disorders. Better understanding of the neural circuitry involved in these abilities will open paths to treatment. In humans and mice, discrimination and adaptation rely on integrity of the hippocampal dentate gyrus (DG) which both receive glutamatergic input from the entorh...

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Literature Corpus work: 4a639863-22a1-5cc4-8853-d6cf31e37505
DOI: 10.1101/2023.01.26.525756

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