Article

Probing function in ligand-gated ion channels without measuring ion transport

2022-03-09

Abstract excerpt

<h4>ABSTRACT</h4> Although the functional properties of ion channels are most accurately assessed using electrophysiological approaches, a number of experimental situations call for alternative methods. Here, working on members of the pentameric ligand-gated ion-channel (pLGIC) superfamily, we focused on the practical implementation of, and the interpretation of results from, equilibrium-type ligand-binding assay...

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Literature Corpus work: 4a627cdb-8690-5b13-b729-0f990b96a043
DOI: 10.1101/2022.03.08.483473

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