Article

Polyclonal expansion of functional tumor-reactive lymphocyte infiltrating glioblastoma for personalized cell therapy

2025-03-05

Abstract excerpt

<title>Abstract</title> <p>Tumor-infiltrating lymphocyte (TIL)-therapy has received FDA approval for the treatment of advanced melanoma and shows potential for broader applications in solid tumors, including glioblastoma. In this study, tumor-reactive TILs (tr-TILs) were isolated and enriched for CD137 expression from cavitron ultrasonic aspirator (CUSA) emulsions of 161 adult patients diagnosed with diffuse glio...

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Literature Corpus work: 4a1faf54-981a-5da4-b95a-abdb3df7f802
DOI: 10.21203/rs.3.rs-6080471/v1

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