Article

Neoadjuvant Triplet Immune Checkpoint Blockade in Newly Diagnosed Glioblastoma

2024-04-29

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM) is an aggressive primary brain tumor with a dismal prognosis. Given the paucity of tumor infiltrating lymphocytes (TILs), an immune suppressive tumor microenvironment and a low tumor mutation burden, the potential benefits of immune checkpoint inhibition (ICI) for GBM patients are considered low<sup>1,2</sup>. Anti-PD-1 ICI monotherapy administered post-primary resect...

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Literature Corpus work: efb6b374-d7ec-5842-83e4-635d34d4a923
DOI: 10.21203/rs.3.rs-4255559/v1

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