Article

EXC-4/CLIC, Gα, and Rho/Rac signaling regulate tubulogenesis in <i>C. elegans</i>

2021-06-21

Abstract excerpt

<h4>ABSTRACT</h4> The Rho-family of small GTPases, which play crucial roles in development and disease, are regulated by many signal-transduction cascades, including G-protein-coupled receptor (GPCR)-heterotrimeric G-protein (Gα/β/γ) pathways. Using genetic approaches in C. elegans we identified a new role for Gα and Rho/Rac signaling in cell outgrowth during tubulogenesis and show that the Chloride Intracellula...

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Literature Corpus work: 4a1b66e1-8c4f-51b6-a7f1-ead24f8aff95
DOI: 10.1101/2021.06.21.449267

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