Article
A putative GDP-GTP exchange factor is required for development of the excretory cell in Caenorhabditis elegans.
EMBO reports - 1 Jun 2001
Suzuki N, Buechner M, Nishiwaki K, Hall D H, Nakanishi H, Takai Y, Hisamoto N, Matsumoto K
Abstract excerpt
The Caenorhabditis elegans excretory cell extends tubular processes, called canals, along the basolateral surface of the epidermis. Mutations in the exc-5 gene cause tubulocystic defects in this canal. Ultrastructural analysis suggests that exc-5 is required for the proper placement of cytoskeletal elements at the apical epithelial surface. exc-5 encodes a protein homologous to guanine nucleotide exchange factors...
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