Article

CRYO-EM STRUCTURE OF THE DELTA-RETROVIRAL INTASOME IN COMPLEX WITH THE PP2A REGULATORY SUBUNIT B56γ

2020-06-20

Abstract excerpt

The Retroviridae delta-retrovirus genus includes the most oncogenic pathogen– human T-cell lymphotropic virus type 1 (HTLV-1)(1). Many of the ~20 million people infected with HTLV-1 will develop severe leukaemia (2) or an ALS-like motor disease (3) unless a therapy becomes available. A key step in the establishment of infection is the integration of viral genetic material into the host genome, catalysed by the vi...

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Literature Corpus work: 49995667-617a-5c06-8cd4-ade3cfe2d196
DOI: 10.1101/2020.06.19.161513

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