Article

Distinct features of a peripheral T-helper subset that drives B cell response in dengue virus infection

2024-02-01

Abstract excerpt

<title>Abstract</title> <p>Dengue virus-induced humoral immunity can enhance the risk of severe disease, but the factors influencing this response are poorly understood. Here, we investigated the contribution of CD4<sup>+</sup> T-cells in driving B-cell response in human dengue-infection. We identified a dominant peripheral PD1<sup>+</sup> T-cell subset that aberrantly accumulated in severe patients and can induc...

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Identifiers and source

Literature Corpus work: 49985db6-7c53-558b-8dbb-ea53f5c92d7c
DOI: 10.21203/rs.3.rs-3886693/v1

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