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Article

ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection.

Nucleic acids research - 9 Sept 2024

Eliad Berta, Schneider Noa, Ben-Naim Zgayer Orna, Amichan Yarden, Glaser Fabian, Erdmann Emily A, Rajendren Suba, Hundley Heather A, Lamm Ayelet T

Abstract excerpt

Adenosine-to-inosine (A-to-I) RNA editing, catalyzed by ADAR enzymes, is a prevalent and conserved RNA modification. While A-to-I RNA editing is essential in mammals, in Caenorhabditis elegans, it is not, making them invaluable for RNA editing research. In C. elegans, ADR-2 is the sole catalytic A-to-I editing enzyme, and ADR-1 is an RNA editing regulator. ADAR localization is well-studied in humans but not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39036970
DOI: 10.1093/nar/gkae641
PMCID: PMC11381337

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection.PMID 39036970Read ↗

ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selectionSemantic proximity Read ↗

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ADARs mediate distinct RNA editing activity and gene regulation in the <i>Caenorhabditis elegans</i> germlineSemantic proximity Read ↗

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