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Article

ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility.

Scientific reports - 14 Jul 2020

Snyder Elizabeth, Chukrallah Lauren, Seltzer Kelly, Goodwin Leslie, Braun Robert E

Abstract excerpt

Adenosine-to-inosine RNA editing, a fundamental RNA modification, is regulated by adenosine deaminase (AD) domain containing proteins. Within the testis, RNA editing is catalyzed by ADARB1 and is regulated in a cell-type dependent manner. This study examined the role of two testis-specific AD domain proteins, ADAD1 and ADAD2, on testis RNA editing and male germ cell differentiation. ADAD1, previously shown to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32665638
DOI: 10.1038/s41598-020-67834-5
PMCID: PMC7360552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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