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Exceptional Mitochondrial Diversity Under Strong Purifying Selection in Admixed Populations, and How Reference Choice Can Mask It.

2026-07-30

Abstract excerpt

Mitochondrial protein-coding genes are compact, functionally constrained, and generally under strong purifying selection, leading to an expectation of few amino acid-altering variants within populations. We characterized variation in the 13 protein-coding genes of 141 Fundulus heteroclitus from three proximate admixed populations each with two ancestral mitochondrial clades. Across 11,417 bp of coding sequence we...

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Literature Corpus work
496d599c-48eb-5787-baa9-6da4d6516d8b
DOI
10.22541/authorea.15006787/v1
Open publication

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