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Article

Similar Efficacies of Selection Shape Mitochondrial and Nuclear Genes in Both Drosophila melanogaster and Homo sapiens.

G3 (Bethesda, Md.) - 21 Aug 2015

Cooper Brandon S, Burrus Chad R, Ji Chao, Hahn Matthew W, Montooth Kristi L

Abstract excerpt

Deleterious mutations contribute to polymorphism even when selection effectively prevents their fixation. The efficacy of selection in removing deleterious mitochondrial mutations from populations depends on the effective population size (Ne) of the mitochondrial DNA and the degree to which a lack of recombination magnifies the effects of linked selection. Using complete mitochondrial genomes from Drosophila...

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Identifiers

PMID: 26297726
DOI: 10.1534/g3.114.016493
PMCID: PMC4592998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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