Article

Genes and sites under adaptation at the phylogenetic scale also exhibit adaptation at the population-genetic scale

2022-09-26

Abstract excerpt

Adaptation in protein-coding sequences can be detected from multiple sequence alignments across species, or alternatively by leveraging polymorphism data inside a population. Across species, quantification of the adaptive rate relies on phylogenetic codon models, classically formulated in terms of the ratio of non-synonymous over synonymous substitution rates. Evidence of an accelerated non-synonymous substitution...

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Literature Corpus work: 3997f3b8-f50f-5a82-b5d4-9ce75ffbfe71
DOI: 10.1101/2022.09.23.509132

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