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Article

Evolved genetic and phenotypic differences due to mitochondrial-nuclear interactions.

PLoS genetics - 1 Mar 2017

Baris Tara Z, Wagner Dominique N, Dayan David I, Du Xiao, Blier Pierre U, Pichaud Nicolas, Oleksiak Marjorie F, Crawford Douglas L

Abstract excerpt

The oxidative phosphorylation (OxPhos) pathway is responsible for most aerobic ATP production and is the only pathway with both nuclear and mitochondrial encoded proteins. The importance of the interactions between these two genomes has recently received more attention because of their potential evolutionary effects and how they may affect human health and disease. In many different organisms, healthy nuclear and...

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PMID: 28362806
DOI: 10.1371/journal.pgen.1006517
PMCID: PMC5375140

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