Article

Novel Analgesic Agents Obtained by Molecular Hybridization of Orthosteric and Allosteric Ligands

2019-12-05

Abstract excerpt

Despite the high incidence of acute and chronic pain in the general population, the efficacy of currently available medications is unsatisfactory. Insufficient management of pain has a profound impact on the quality of life and can have serious physical, psychological, social, and economic consequences. This unmet need reflects a failure to develop novel classes of analgesic drugs with superior clinical properties...

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Literature Corpus work: 4955b154-932f-529d-a5af-cfec404c7bee
DOI: 10.1101/866012

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