Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A flow cytometry-based screen for synthetic riboswitches.

Nucleic acids research - 1 Jan 2009

Lynch Sean A, Gallivan Justin P

Abstract excerpt

Riboswitches regulate gene expression through direct, small molecule-mRNA interactions. The creation of new synthetic riboswitches from in vitro selected aptamers benefits from rapid, high-throughput methods for identifying switches capable of triggering dramatic changes in gene expression in the presence of a desired ligand. Here we present a flow cytometry-based screen for identifying synthetic riboswitches...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Aptamers, Nucleotide
Share to Cell Separation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Genes, Reporter

Share to Regulatory Sequences, Ribonucleic Acid

Share to Ribosomes

Share to Theophylline

Source

Open in PubMed Open full text

Identifiers

PMID: 19033367
DOI: 10.1093/nar/gkn924
PMCID: PMC2615613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A flow cytometry-based screen for synthetic riboswitches.PMID 19033367Read ↗

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial SpeciesSemantic proximity Read ↗

Generation of orthogonally selective bacterial riboswitches by targeted mutagenesis and in vivo screening.Semantic proximity Read ↗

Riboswitches in unexpected places--a synthetic riboswitch in a protein coding region.Semantic proximity Read ↗

A unique mechanism explaining the outstanding performance of a newly discovered doxycycline riboswitchSemantic proximity Read ↗

Rational design of a synthetic mammalian riboswitch as a ligand-responsive -1 ribosomal frame-shifting stimulatorSemantic proximity Read ↗

Requirements for efficient ligand-gated co-transcriptional switching in designed variants of the B. subtilis pbuE adenine-responsive riboswitch in E. coli.Semantic proximity Read ↗

High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ <sub>1</sub> riboswitch ligandsSemantic proximity Read ↗

Systematic Mutation and Unnatural Base Pair Incorporation Improves Riboswitch-Based Biosensor Response Time.Semantic proximity Read ↗

Engineering complex riboswitch regulation by dual genetic selection.Semantic proximity Read ↗

Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations.Semantic proximity Read ↗

Tuning a riboswitch response through structural extension of a pseudoknot.Semantic proximity Read ↗

Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral VectorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.