Article

Multi-ancestry Genome-wide Association Study of Creatine Kinase Highlights the Genetic Basis of Muscle Damage

2025-09-25

Abstract excerpt

Serum creatine kinase (CK) is a routinely measured biomarker of muscle damage, yet the genetic factors underlying inter-individual variation in CK levels remain poorly defined. Here we present the largest multi-ancestry genome-wide association meta-analysis of serum CK to date, comprising 237,255 participants spanning Admixed American, African American, East Asian, European and Middle Eastern populations. We ident...

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Literature Corpus work: 49142bdf-30f6-5c98-9596-49dba3174d0c
DOI: 10.1101/2025.09.24.25335552

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