Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CKM and LILRB5 are associated with serum levels of creatine kinase.

Circulation. Cardiovascular genetics - 1 Dec 2014

Dubé Marie-Pierre, Zetler Rosa, Barhdadi Amina, Brown Andrew M K, Mongrain Ian, Normand Valérie, Laplante Nathalie, Asselin Géraldine, Zada Yassamin Feroz, Provost Sylvie, Bergeron Jean, Kouz Simon, Dufour Robert, Diaz Ariel, de Denus Simon, Turgeon Jacques, Rhéaume Eric, Phillips Michael S, Tardif Jean-Claude

Abstract excerpt

BACKGROUND: Statins (HMG-CoA reductase inhibitors) are the most prescribed class of lipid-lowering drugs for the treatment and prevention of cardiovascular disease. Creatine kinase (CK) is a commonly used biomarker to assist in the diagnosis of statin-induced myotoxicity but the normal range of CK concentrations is wide, which limits its use as a diagnostic biomarker. METHODS AND RESULTS: We conducted a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Creatine Kinase

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hyperlipidemias

Share to Linkage Disequilibrium

Share to Protein Serine-Threonine Kinases

Share to Receptors, Immunologic

Source

Identifiers

PMID: 25214527
DOI: 10.1161/CIRCGENETICS.113.000395

Genes

CKM
LILRB5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CKM and LILRB5 are associated with serum levels of creatine kinase.PMID 25214527Read ↗

Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic review.Semantic proximity Read ↗

Multi-ancestry genome-wide association study of serum creatine kinase implicates myopathy genes and muscle pathways.Semantic proximity Read ↗

Genetic Determinants of Statin-induced Myopathy: A Network Meta-analysis of Observational Studies.Semantic proximity Read ↗

Multi-ancestry Genome-wide Association Study of Creatine Kinase Highlights the Genetic Basis of Muscle DamageSemantic proximity Read ↗

Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management.Semantic proximity Read ↗

Association between statin-induced creatine kinase elevation and genetic polymorphisms in SLCO1B1, ABCB1 and ABCG2.Semantic proximity Read ↗

Statin-Related Myotoxicity: A Comprehensive Review of Pharmacokinetic, Pharmacogenomic and Muscle ComponentsSemantic proximity Read ↗

Statin myotoxicity: a review of genetic susceptibility factors.Semantic proximity Read ↗

A common missense variant of LILRB5 is associated with statin intolerance and myalgia.Semantic proximity Read ↗

RYR1 and CACNA1S genetic variants identified with statin-associated muscle symptomsSemantic proximity Read ↗

Uncovering Coenzyme Q10-Related Genetic Determinants of Statin-Associated Muscle Symptoms: Evidence from the UK Biobank and the All of Us Research Program.Semantic proximity Read ↗

Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research DatalinkSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.