Article

Psychomotor Impairments and Therapeutic Implications Revealed by a Mutation Associated with Infantile Parkinsonism-Dystonia

2021-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson disease (PD) is a progressive, neurodegenerative disorder affecting over 6.1 million people worldwide. Although the cause of PD remains unclear, studies of highly-penetrant mutations identified in early-onset familial parkinsonism have contributed to our understanding of the molecular mechanisms underlying disease pathology. Dopamine (DA) transporter (DAT) deficiency syndrome (DTDS) is...

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Literature Corpus work: 48b72a3c-7101-54e3-b8cc-32cd98864579
DOI: 10.1101/2021.03.09.434693

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