Article

Single-Cell Analysis of Hyperthermic Intraperitoneal Chemotherapy Treated Tumors Reveals Distinct Cellular and Molecular Responses

2020-10-07

Abstract excerpt

<h4>Summary</h4> Hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a clinical regimen that prolongs overall survival for patients with advanced Epithelial Ovarian Cancer (EOC). However, the mechanism of action of HIPEC remains poorly understood. To provide insights into the rapid changes that accompany HIPEC, tumors from five patients with high grade serous ovarian cancer were harvested from the om...

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Literature Corpus work: 48507751-fdcd-5f07-a73e-3694364f1c42
DOI: 10.1101/2020.10.05.326710

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