Article

Transcriptomic evaluation of immune-infiltrated patient-derived tumor organoids as preclinical models in renal cell carcinoma

2026-02-01

Abstract excerpt

Patient-derived tumor organoids (PDTOs) have emerged as valuable preclinical models for studying tumor biology and therapeutic responses. However, despite the development of protocols for tumor dissociation and immune cell infiltration, their fidelity in representing clear cell renal cell carcinoma (ccRCC) tumors remains poorly characterized. To address this, we established matched samples, including tumor tissue,...

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Literature Corpus work: f711114b-0f9d-5082-bea8-919cc56930b3
DOI: 10.64898/2026.01.28.699468

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