Article

ASMS: finding allele specific methylation in human genomes without phasing

2024-12-22

Abstract excerpt

<h4>Motivation</h4> Allele-specific methylation (ASM) refers to differential DNA methylation patterns between two alleles at a given locus. This phenomenon is often driven by genetic variants, such as single nucleotide variants (SNVs), which influence methylation in cis by affecting transcription factor or methylation regulator binding, leading to allele-specific differences. Understanding ASM is critical for el...

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Literature Corpus work: 5de37be1-95ab-554f-9c9a-f26955080187
DOI: 10.1101/2024.12.18.629129

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