Article

EIF3H Regulates ERK-Driven Oncogenic Signaling in Breast Cancer Metastasis

2025-08-28

Abstract excerpt

Breast cancer remains a leading cause of cancer-related mortality among women, with metastasis being the primary driver of poor prognosis. The ubiquitin–proteasome system (UPS) is a central regulator of protein homeostasis, and its dysregulation is associated with multiple cancers. Within this system, deubiquitinating enzymes (DUBs), which remove ubiquitin moieties from target proteins and thereby modulate their s...

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Identifiers and source

Literature Corpus work: 4834a714-d451-564d-a0f2-24a2c7e94724
DOI: 10.1101/2025.08.24.672041

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